Inflammatory markers in COPD
نویسندگان
چکیده
منابع مشابه
Symptom profiles and inflammatory markers in moderate to severe COPD
BACKGROUND Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS We conducted latent class analyses of three physical (dyspnea, fatigue, and...
متن کاملSystemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study.
Chronic obstructive pulmonary disease (COPD) is considered an inflammatory pulmonary disorder with systemic inflammatory manifestations. The aim of this study was to assess the systemic levels of six inflammatory mediators in a large cohort of COPD patients and controls. 409 COPD patients and 231 healthy subjects, aged 40-75 yrs, were included from the first phase of the Bergen COPD Cohort Stud...
متن کاملComparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients
BACKGROUND Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways. Whether spontaneously sampled sputum can be a valid surrogate is unknown. The aim of this study was to compare levels of six inflammatory markers in sputum pairs consisting of induced and spontaneous sputum sampled on the same consultation either in a stable state or during exacerbati...
متن کاملEffect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD.
Chronic obstructive pulmonary disease (COPD) patients experiencing frequent exacerbations demonstrate increased stable-state airway inflammation. Tiotropium has been shown to reduce exacerbation frequency, but its effect on airway inflammation is unknown. The aim of the present study was to investigate the effect of tiotropium on sputum inflammatory markers and exacerbation frequency. Patients ...
متن کاملRelation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations.
BACKGROUND Although it is presumed that exacerbations of chronic obstructive pulmonary disease (COPD) are associated with increased airway inflammation, there is little information available on inflammatory markers during an exacerbation and the relationship with severity or time course of recovery. A study was undertaken to investigate the sputum cell and cytokine characteristics of COPD when ...
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ژورنال
عنوان ژورنال: The Clinical Respiratory Journal
سال: 2008
ISSN: 1752-6981
DOI: 10.1111/j.1752-699x.2008.00089.x